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It is usually recommended to drink some alcohol immediately after (not prior) to the Nembutal ingestion to potentiate its effect and mask the very bitter taste. Eating a big meal prior to or after the drug ingestion is not recommended to reduce chances of slow drug absorption or vomiting. Dignitas offers clients chocolates to deal with the bitter taste of the drug.
Experience in the world has notified that after ingesting 20 grams to 50 grams of either nembutal powder or lethal, death generally occurs within few hours and depending of the age and weight of the subject.
